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History:
Doxycycline invented and first patented in 1960s by Pfizer Inc. company. Under brand name «Vibramycin», this product received US FDA approval in 1967. Doxycycline is available worldwide now.
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Doxycycline is a member of the semi-synthetic tetracycline antibiotics group. This product is commonly used to treat a variety of infections - urinary tract infections, acne, sinusitis, syphilis, gonorrhea, and chlamydia, periodontitis (gum disease), chronic prostatitis, pelvic inflammatory disease, and others. Worldwide brand names - Vibramycin, Periostat, Monodox, Microdox, Vibra-Tabs, Doryx, Vibrox, Adoxa, Oracea, Doxyhexal, Atridox and Doxylin.Generic Doxycycline (like any other antibiotic) works by slowing the growth of bacteria in the body.
Generic Doxycycline (Doryx) is Delayed-Release Tablets, for oral administration. This product contain specially coated pellets of doxycycline hyclate, a broad-spectrum antibiotic synthetically derived from oxytetracycline, in a delayed-release formulation for oral administration.
Do not use this drug during pregnancy, because it could cause harm to the unborn baby, including permanent discoloration of the teeth later in life. Also this antibiotic can make birth control pills less effective. It passes into breast milk and may affect bone and tooth development in a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.
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Because antibiotic have been shown to depress plasma prothrombin activity, peoples who are on anticoagulant therapy may require downward tune of their anticoagulant dosage. Follow the procedures you are taught when you use a dose. It is usually given as an injection at your doctor's office, clinic or hospital. If you will be using Doxycycline at home, a health care provider will teach you how to use it. Contact your health care provider if you have any questions.The concurrent use of tetracycline and methoxyflurane has been reported to result in fatal renal toxicity. Since bacteriostatic drugs may interfere with the bactericidal action of penicillin. It is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. Absorption of Doxycycline is impaired by bismuth subsalicylate, proton pump inhibitors, antacids containing aluminum, calcium or magnesium and iron-containing preparations.
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Adverse Reactions for this drugs: The following adverse reactions have been observed in patients receiving tetracyclines at higher, antimicrobial doses: Gastrointestinal: anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with vaginal candidiasis) in the anogenital region. Rare instances of esophagitis and esophageal ulcerations have been reported in patients receiving the capsule forms of the Cheap Doxycycline in the tetracycline class. Hepatotoxicity has been reported rarely.Most of the patients experiencing esophagitis and/or esophageal ulceration took their medication immediately before lying down. Skin: maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Photosensitivity is discussed above. (See WARNINGS section).